Right click on Computer after that click on properties.
Click on ''Advanced System Settings'' and System Properties will appear.
Click on "Advanced" after that "Settings" , Performance Option will appear.
Click on "Data Execution Prevention" and Turn on the "Turn on DEP for all Programs.
Click on add and add your gta_sa.exe and samp. At last "Apply".
Restart your computer.
If you need a tutorial, then I can provide it by myself.
Did you try all of the solves? But nothing solves? For these runtime error's last solution is only creating another new account in your PC.